The Molecular-Cellular World of Dental Tissues

Intradental Mechanoception and Transduction at the Core of Occlusal Medicine (VIESID Summer School 2025)

This page provides the full list of scientific references cited in MUDr. Radmila Sedlacková, MSc. poster:

"The Molecular-Cellular World of Dental Tissues: Intradental Mechanoception and Transduction — The Core of Occlusal Medicine".

Presented 23–27 July 2025 at the VIESID Summer School 2025 — A Journey Through the Rehabilitation of Occlusion.

The references reflect current insights into the histology, ultrastructure, and sensory mechanisms of dental tissues relevant for occlusal medicine. We encourage visitors to explore these original sources for further detail.

1. Ogita Y, Iwai-Liao Y, Higashi Y. A histological study of the organic elements in the human enamel focusing on the extent of the odontoblast process. Okajimas Folia Anat Jpn. 1998;74(6):317-327. DOI (free accces): 10.2535/ofaj1936.74.6_317

2. Whittaker DK. The enamel-dentin junction of human and Macaca irus teeth: a light and electron microscopic study. J Anat. 1978;125(2):323-335.  PMCID: PMC1235600

3. Solé-Magdalena A, Martínez-Alonso M, Coronado CA, Junquera LM, Cobos J, Vega JA. Molecular basis of dental sensitivity: the odontoblasts are multisensory cells and express multifunctional ion channels. Ann Anat. 2018;215:20-29. DOI: https://doi.org/10.1016/j.aanat.2017.09.006

4. Levy JH. Ultrastructural deformations and proprioceptive function in human teeth [dissertation]. New York: New York University College of Dentistry; 1994. (web page of the practice: https://www.jayharrislevy.com/)

5. Lin Y, Ren J, McGrath C. Mechanosensitive Piezo1 and Piezo2 ion channels in craniofacial development and dentistry: recent advances and prospects. Front Physiol. 2021;12:709220. DOI: 10.3389/fphys.2022.1039714

6. Křivánek J. Molecular-morphological study of odontoblasts and their differentiation from human embryonic stem cells [doctoral thesis]. Vienna: Medical University of Vienna; Brno: Masaryk University; 2018. https://is.muni.cz/th/lbnks/?lang=en#paneltext

7. Roth, Bradley J. "A Mathematical Model of Mechanotransduction." Academia Biology, vol. 1, no. 1, Academia.edu Journals, 2023, doi:10.20935/AcadBiol6081.

8. Patapoutian A. How do you feel? The molecules that sense touch. Nobel Lecture. 2021 Dec 7. Scripps Research, La Jolla, CA. https://www.nobelprize.org/uploads/2021/12/patapoutian-lecture.pdf